1-Methyl-3-phenylthiourea

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1-Methyl-3-phenyl­thio­urea

The title compound, C8H10N2S, was prepared by reaction of methyl-amine solution, KOH and phenyl-iso-thio-cyanate in ethanol. It adopts a syn-Me and anti-Ph conformation relative to the C=S double bond. The dihedral angle between the N-C(=S)-N thio-urea and phenyl planes is 67.83 (6)°. In the crystal, the mol-ecules centrosymmetrical dimers by pairs of N(Ph)-H⋯S hydrogen bonds. The dimers are li...

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1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.

New 1-benzhydryl-3-phenylurea derivatives and their 1-benzhydryl-3-phenylthiourea isosteres were synthesized and evaluated for their human CB1 and CB2 cannabinoid receptor affinity. These compounds proved to be selective CB1 cannabinoid receptor ligands, acting as inverse agonists in a [35S]-GTPgammaS assay. The affinity of 3,5,5'-triphenylimidazolidine-2,4-dione and 3,5,5'-triphenyl-2-thioxoim...

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1-Benzoyl-3-methyl-3-pentyl­thio­urea

Two independent mol-ecules comprise the asymmetric unit of the title compound, C(14)H(20)N(2)OS. These differ in the relative orientations of the pentyl chains [C-C-C-C torsion angles = -176.7 (3) and 176.4 (3)°]. Significant twists are evident in each mol-ecule, the dihedral angles formed between the thio-urea and amide residues being 53.47 (17) and 55.81 (17)°. In the crystal, each mol-ecule ...

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1-Furoyl-3-methyl-3-phenyl­thio­urea

The title compound, C(13)H(12)N(2)O(2)S, crystallizes with two independent mol-ecules in the asymmetric unit. The two mol-ecules differ in the conformation of the thio-carbonyl and carbonyl groups, and show the typical geometric parameters of substituted thio-urea derivatives. The crystal structure is mainly stabilized by inter-molecular N-H⋯O hydrogen bonding.

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3-O-Methyl-1-isomangostin

IN THE TITLE XANTHONE DERIVATIVE [SYSTEMATIC NAME: 9-hy-droxy-5,10-dimeth-oxy-2,2-dimethyl-11-(3-methyl-but-2-en-1-yl)-2,3,4,12-tetra-hydro-1,7-dioxatetra-phen-12-one], C(25)H(28)O(6), the xanthone ring system is roughly planar, with an r.m.s. deviation of 0.1038 (1) Å. The chromane ring is in a half-chair conformation and the 3-methyl-but-2-enyl substituent is axially attached with an (+)-anti...

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ژورنال

عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online

سال: 2014

ISSN: 1600-5368

DOI: 10.1107/s1600536814007442